CDK9
cyclin-dependent kinase 9
Synonyms:
C-2k, CDC2L4, CTK1, PITALRE, TAK
Species:
Human CDK9 (1025), Mouse Cdk9 (107951), Rat Cdk9 (362110), domestic guinea pig Cdk9 (100725846), naked mole-rat Cdk9 (101722666), sheep CDK9 (101109788), Zebrafish cdk9 (321602), cow CDK9 (520580), dog CDK9 (491325), chicken CDK9 (417226) ...More
UniProtKB ID:
Gene ID:
- Human(1025) Summary: The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, and known as important cell cycle regulators. This kinase was found to be a component of the multiprotein complex TAK/P-TEFb, which is an elongation factor for RNA polymerase II-directed transcription and functions by phosphorylating the C-terminal domain of the largest subunit of RNA polymerase II. This protein forms a complex with and is regulated by its regulatory subunit cyclin T or cyclin K. HIV-1 Tat protein was found to interact with this protein and cyclin T, which suggested a possible involvement of this protein in AIDS. [provided by RefSeq, Jul 2008]
- Mouse(107951) cyclin-dependent kinase 9 (CDC2-related kinase)
- Rat(362110) cyclin-dependent kinase 9
- domestic guinea pig(100725846) cyclin-dependent kinase 9
- naked mole-rat(101722666) cyclin-dependent kinase 9
- sheep(101109788) cyclin-dependent kinase 9
- Zebrafish(321602) cyclin-dependent kinase 9 (CDC2-related kinase)
- cow(520580) cyclin-dependent kinase 9
- dog(491325) cyclin-dependent kinase 9
- chicken(417226) cyclin-dependent kinase 9
- fruit fly(37586) Cyclin-dependent kinase 9
- domestic cat(101097767) cyclin-dependent kinase 9
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-CDK9, (N-terminal) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
immunohistochemistry
western blot
western blot
Rabbit anti-CDK9 Antibody, Affinity Purified, Powered by Bethyl Laboratories, Inc.,
Species Reactivity
human, mouse
Application
immunohistochemistry
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Anti-phospho-CDK9 (pThr186) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
western blot
western blot
Monoclonal Anti-CDK9, (C-terminal) antibody produced in mouse, clone 2D7, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence
western blot
immunofluorescence
western blot
Small Molecule - Inhibitor
Proteins
Product Number
Description
Species
CDK9/CyclinK, active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human