CCNDBP1
cyclin D-type binding-protein 1
Synonyms:
DIP1, GCIP, HHM
Species:
Human CCNDBP1 (23582), Mouse Ccndbp1 (17151), Rat Ccndbp1 (362201), sheep CCNDBP1 (101120086), chicken CCNDBP1 (419217), cow CCNDBP1 (617512), dog CCNDBP1 (607896), domestic guinea pig Ccndbp1 (100723755), naked mole-rat Ccndbp1 (101715315), domestic cat CCNDBP1 (101100394)
UniProtKB ID:
Gene ID:
- Human(23582) Summary: This gene was identified by the interaction of its gene product with Grap2, a leukocyte-specific adaptor protein important for immune cell signaling. The protein encoded by this gene was shown to interact with cyclin D. Transfection of this gene in cells was reported to reduce the phosphorylation of Rb gene product by cyclin D-dependent protein kinase, and inhibit E2F1-mediated transcription activity. This protein was also found to interact with helix-loop-helix protein E12 and is thought to be a negative regulator of liver-specific gene expression. Several alternatively spliced variants have been found for this gene. [provided by RefSeq, Apr 2009]
- Mouse(17151) cyclin D-type binding-protein 1
- Rat(362201) cyclin D-type binding-protein 1
- sheep(101120086) cyclin D-type binding-protein 1
- chicken(419217) cyclin D-type binding-protein 1
- cow(617512) cyclin D-type binding-protein 1
- dog(607896) cyclin D-type binding-protein 1
- domestic guinea pig(100723755) cyclin D-type binding-protein 1
- naked mole-rat(101715315) cyclin D-type binding-protein 1
- domestic cat(101100394) cyclin D-type binding-protein 1
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