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Merck

CACNA1G

calcium channel, voltage-dependent, T type, alpha 1G subunit

Synonyms:
Ca(V)T.1, Cav3.1, NBR13
Species:
UniProtKB ID:
Gene ID:
  • Human(8913) Summary: Voltage-sensitive calcium channels mediate the entry of calcium ions into excitable cells, and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division, and cell death. This gene encodes a T-type, low-voltage activated calcium channel. The T-type channels generate currents that are both transient, owing to fast inactivation, and tiny, owing to small conductance. T-type channels are thought to be involved in pacemaker activity, low-threshold calcium spikes, neuronal oscillations and resonance, and rebound burst firing. Many alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Sep 2011]
  • Mouse(12291) calcium channel, voltage-dependent, T type, alpha 1G subunit
  • Rat(29717) calcium channel, voltage-dependent, T type, alpha 1G subunit
  • cow(282411) calcium channel, voltage-dependent, T type, alpha 1G subunit
  • domestic guinea pig(100728128) calcium channel, voltage-dependent, T type, alpha 1G subunit
  • Zebrafish(563904) calcium channel, voltage-dependent, T type, alpha 1G subunit
  • sheep(101117004) calcium channel, voltage-dependent, T type, alpha 1G subunit
  • naked mole-rat(101709921) calcium channel, voltage-dependent, T type, alpha 1G subunit
  • dog(491083) calcium channel, voltage-dependent, T type, alpha 1G subunit
  • Domestic Rabbit(100346309) calcium channel, voltage-dependent, T type, alpha 1G subunit
  • chicken(769385) calcium channel, voltage-dependent, T type, alpha 1G subunit
  • Horse(100070000) calcium channel, voltage-dependent, T type, alpha 1G subunit
  • domestic cat(101098757) calcium channel, voltage-dependent, T type, alpha 1G subunit

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Small Molecule - Allosteric Modulator

Product Number
Description
Species
Gabapentin, Pharmaceutical Secondary Standard; Certified Reference Material,
Species
human
Pregabalin, European Pharmacopoeia (EP) Reference Standard,
Species
human
Gabapentin, European Pharmacopoeia (EP) Reference Standard,
Species
human
Gabapentin, solid,
Species
human, rat

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-CACNA1G antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
dog, horse, human, rabbit
Application
immunohistochemistry
western blot
Monoclonal Anti-Cav3.1 antibody produced in mouse, clone S178A-9, purified immunoglobulin,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot
Anti-Calcium Channel CaV3.1 (α1G) antibody produced in rabbit, affinity isolated antibody, lyophilized powder,
Species Reactivity
rat
Application
western blot
Anti-Calcium Channel (α1G Subunit) (T-type Voltage-Gated Ca2+ Channel) antibody produced in rabbit, ~1 mg/mL, fractionated antiserum, buffered aqueous solution,
Species Reactivity
human, mouse, rat
Application
western blot

Small Molecule - Blocker

Product Number
Description
Species
Ethosuximide, ,
Species
human
Ethosuximide, Pharmaceutical Secondary Standard; Certified Reference Material,
Species
human
Ethosuximide, analytical standard,
Species
human
Ethosuximide, European Pharmacopoeia (EP) Reference Standard,
Species
human
Trimethadione, European Pharmacopoeia (EP) Reference Standard,
Species
human

Small Molecule - Ligand

Product Number
Description
Species
Ethosuximide, ,
Species
human
Gabapentin, solid,
Species
human, rat