CACNA1F
calcium channel, voltage-dependent, L type, alpha 1F subunit
Synonyms:
AIED, COD3, COD4, CORDX, CORDX3, CSNB2, CSNB2A, CSNBX2, Cav1.4, Cav1.4alpha1, JM8, JMC8, OA2
Species:
Human CACNA1F (778), Mouse Cacna1f (54652), Rat Cacna1f (114493), sheep CACNA1F (101104552), naked mole-rat Cacna1f (101722090), domestic guinea pig Cacna1f (100720484), Zebrafish cacna1f (386662), domestic cat CACNA1F (101080870), dog CACNA1F (480915), cow CACNA1F (509779)
UniProtKB ID:
Gene ID:
- Human(778) Summary: This gene encodes a member of the alpha-1 subunit family; a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. The alpha-1 subunit has 24 transmembrane segments and forms the pore through which ions pass into the cell. There are multiple isoforms of each of the proteins in the complex, either encoded by different genes or the result of alternative splicing of transcripts. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. Mutations in this gene have been shown to cause incomplete X-linked congential stationary night blindness type 2 (CSNB2). [provided by RefSeq, Feb 2012]
- Mouse(54652) calcium channel, voltage-dependent, alpha 1F subunit
- Rat(114493) calcium channel, voltage-dependent, L type, alpha 1F subunit
- sheep(101104552) calcium channel, voltage-dependent, L type, alpha 1F subunit
- naked mole-rat(101722090) calcium channel, voltage-dependent, L type, alpha 1F subunit
- domestic guinea pig(100720484) calcium channel, voltage-dependent, L type, alpha 1F subunit
- Zebrafish(386662) calcium channel, voltage-dependent, alpha 1F subunit
- domestic cat(101080870) calcium channel, voltage-dependent, L type, alpha 1F subunit
- dog(480915) calcium channel, voltage-dependent, L type, alpha 1F subunit
- cow(509779) calcium channel, voltage-dependent, L type, alpha 1F subunit
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Small Molecule - Allosteric Modulator
Product Number
Description
Species
Small Molecule - Blocker
Product Number
Description
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Amlodipine besylate, Pharmaceutical Secondary Standard; Certified Reference Material,
Species
human