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Merck

BMPR1A

bone morphogenetic protein receptor, type IA

Synonyms:
10q23del, ACVRLK3, ALK3, CD292, SKR5
Species:
Human BMPR1A (657), Mouse Bmpr1a (12166), Rat Bmpr1a (81507), Goat BMPR1A (100861241), Domestic Rabbit BMPR1A (100350518), sheep BMPR1A (101112282), dog BMPR1A (489077), cow BMPR1A (404101), domestic cat BMPR1A (101089548), naked mole-rat Bmpr1a (101700899) ...More
UniProtKB ID:
P36894, A8K6U9, Q8NEN8
Gene ID:
  • Human(657) Summary: The bone morphogenetic protein (BMP) receptors are a family of transmembrane serine/threonine kinases that include the type I receptors BMPR1A and BMPR1B and the type II receptor BMPR2. These receptors are also closely related to the activin receptors, ACVR1 and ACVR2. The ligands of these receptors are members of the TGF-beta superfamily. TGF-betas and activins transduce their signals through the formation of heteromeric complexes with 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. [provided by RefSeq, Jul 2008]
  • Mouse(12166) bone morphogenetic protein receptor, type 1A
  • Rat(81507) bone morphogenetic protein receptor, type IA
  • Goat(100861241) bone morphogenetic protein receptor, type IA
  • Domestic Rabbit(100350518) bone morphogenetic protein receptor, type IA
  • sheep(101112282) bone morphogenetic protein receptor, type IA
  • dog(489077) bone morphogenetic protein receptor, type IA
  • cow(404101) bone morphogenetic protein receptor, type IA
  • domestic cat(101089548) bone morphogenetic protein receptor, type IA
  • naked mole-rat(101700899) bone morphogenetic protein receptor, type IA
  • chicken(396308) bone morphogenetic protein receptor, type IA
  • Horse(100064367) bone morphogenetic protein receptor, type IA
  • domestic guinea pig(100723350) bone morphogenetic protein receptor, type IA

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