Skip to Content
Merck

BAG3

BCL2-associated athanogene 3

Synonyms:
BAG-3, BIS, CAIR-1, MFM6
Species:
Human BAG3 (9531), Mouse Bag3 (29810), Rat Bag3 (293524), chicken BAG3 (423931), sheep BAG3 (101108530), Zebrafish bag3 (445139), Thale Cress BAG3 (830613), domestic guinea pig Bag3 (100715844), naked mole-rat Bag3 (101716547), Horse BAG3 (100065784) ...More
UniProtKB ID:
O95817, A8K5L8, Q3B763, Q9NT20, Q9P120
Gene ID:
  • Human(9531) Summary: BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The protein encoded by this gene contains a WW domain in the N-terminal region and a BAG domain in the C-terminal region. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner. [provided by RefSeq, Jul 2008]
  • Mouse(29810) BCL2-associated athanogene 3
  • Rat(293524) Bcl2-associated athanogene 3
  • chicken(423931) BCL2-associated athanogene 3
  • sheep(101108530) BCL2-associated athanogene 3
  • Zebrafish(445139) BCL2-associated athanogene 3
  • Thale Cress(830613) BCL-2-associated athanogene 3
  • domestic guinea pig(100715844) BCL2-associated athanogene 3
  • naked mole-rat(101716547) BCL2-associated athanogene 3
  • Horse(100065784) BCL2-associated athanogene 3
  • domestic cat(101094211) BCL2-associated athanogene 3
  • dog(486916) BCL2-associated athanogene 3
  • cow(782633) BCL2-associated athanogene 3

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Product Number
Description
Species Reactivity
Application
SAB1404732
Monoclonal Anti-BAG3 antibody produced in mouse, clone 5A8, ascites fluid,
Species Reactivity
human
Application
ELISA
western blot
SAB2103926
Anti-BAG3 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, dog, guinea pig, human, mouse, rabbit, rat
Application
western blot