ATP2B1
ATPase, Ca++ transporting, plasma membrane 1
Synonyms:
PMCA1, PMCA1kb
Species:
Human ATP2B1 (490), Mouse Atp2b1 (67972), Rat Atp2b1 (29598), naked mole-rat Atp2b1 (101725886), domestic guinea pig Atp2b1 (100337638), dog ATP2B1 (403480), cow ATP2B1 (282641), domestic cat ATP2B1 (101098392), Domestic Rabbit ATP2B1 (100009543), Horse ATP2B1 (100051636) ...More
UniProtKB ID:
Gene ID:
- Human(490) Summary: The protein encoded by this gene belongs to the family of P-type primary ion transport ATPases characterized by the formation of an aspartyl phosphate intermediate during the reaction cycle. These enzymes remove bivalent calcium ions from eukaryotic cells against very large concentration gradients and play a critical role in intracellular calcium homeostasis. The mammalian plasma membrane calcium ATPase isoforms are encoded by at least four separate genes and the diversity of these enzymes is further increased by alternative splicing of transcripts. The expression of different isoforms and splice variants is regulated in a developmental, tissue- and cell type-specific manner, suggesting that these pumps are functionally adapted to the physiological needs of particular cells and tissues. This gene encodes the plasma membrane calcium ATPase isoform 1. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
- Mouse(67972) ATPase, Ca++ transporting, plasma membrane 1
- Rat(29598) ATPase, Ca++ transporting, plasma membrane 1
- naked mole-rat(101725886) ATPase, Ca++ transporting, plasma membrane 1
- domestic guinea pig(100337638) ATPase, Ca++ transporting, plasma membrane 1
- dog(403480) ATPase, Ca++ transporting, plasma membrane 1
- cow(282641) ATPase, Ca++ transporting, plasma membrane 1
- domestic cat(101098392) ATPase, Ca++ transporting, plasma membrane 1
- Domestic Rabbit(100009543) ATPase, Ca++ transporting, plasma membrane 1
- Horse(100051636) ATPase, Ca++ transporting, plasma membrane 1
- sheep(101111268) ATPase, Ca++ transporting, plasma membrane 1
- chicken(374244) ATPase, Ca++ transporting, plasma membrane 1
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.