ATP1B1
ATPase, Na+/K+ transporting, beta 1 polypeptide
Synonyms:
ATP1B
Species:
Human ATP1B1 (481), Mouse Atp1b1 (11931), Rat Atp1b1 (25650), cow ATP1B1 (519758), Domestic Rabbit ATP1B1 (100008749), Horse ATP1B1 (100033968), naked mole-rat Atp1b1 (101701102), chicken ATP1B1 (396529), dog ATP1B1 (403966), domestic cat ATP1B1 (101081858) ...More
UniProtKB ID:
Gene ID:
- Human(481) Summary: The protein encoded by this gene belongs to the family of Na+/K+ and H+/K+ ATPases beta chain proteins, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane. The glycoprotein subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes a beta 1 subunit. Alternatively spliced transcript variants encoding different isoforms have been described, but their biological validity is not known. [provided by RefSeq, Mar 2010]
- Mouse(11931) ATPase, Na+/K+ transporting, beta 1 polypeptide
- Rat(25650) ATPase, Na+/K+ transporting, beta 1 polypeptide
- cow(519758) ATPase, Na+/K+ transporting, beta 1 polypeptide
- Domestic Rabbit(100008749) ATPase, Na+/K+ transporting, beta 1 polypeptide
- Horse(100033968) ATPase, Na+/K+ transporting, beta 1 polypeptide
- naked mole-rat(101701102) ATPase, Na+/K+ transporting, beta 1 polypeptide
- chicken(396529) ATPase, Na+/K+ transporting, beta 1 polypeptide
- dog(403966) ATPase, Na+/K+ transporting, beta 1 polypeptide
- domestic cat(101081858) ATPase, Na+/K+ transporting, beta 1 polypeptide
- sheep(443384) ATPase, Na+/K+ transporting, beta 1 polypeptide
- domestic guinea pig(100135483) ATPase, Na+/K+ transporting, beta 1 polypeptide
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-ATP1B1 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
bovine, canine, human, mouse, pig, rat
Application
ELISA
western blot
western blot
Anti-ATP1B1 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot
western blot
Small Molecule - Inhibitor
Product Number
Description
Species
Digoxin, certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland,
Species
human
Proteins
Product Number
Description
Species
Adenosine 5′-Triphosphatase from porcine cerebral cortex, lyophilized powder, ≥0.3 units/mg protein, pH 7.8,
Species