ARAP2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
Synonyms:
CENTD1, PARX
Species:
Human ARAP2 (116984), Mouse Arap2 (212285), Rat Arap2 (305367), sheep ARAP2 (101109800), cow ARAP2 (512010), Horse ARAP2 (100065339), domestic cat ARAP2 (101096980), dog ARAP2 (488840), chicken ARAP2 (428790), naked mole-rat Arap2 (101709490)
UniProtKB ID:
Gene ID:
- Human(116984) Summary: The protein encoded by this gene contains ARF-GAP, RHO-GAP, ankyrin repeat, RAS-associating, and pleckstrin homology domains. The protein is a phosphatidylinositol (3,4,5)-trisphosphate-dependent Arf6 GAP that binds RhoA-GTP, but it lacks the predicted catalytic arginine in the RHO-GAP domain and does not have RHO-GAP activity. The protein associates with focal adhesions and functions downstream of RhoA to regulate focal adhesion dynamics. [provided by RefSeq, Sep 2008]
- Mouse(212285) ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
- Rat(305367) ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
- sheep(101109800) ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
- cow(512010) ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
- Horse(100065339) ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
- domestic cat(101096980) ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
- dog(488840) ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
- chicken(428790) ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
- naked mole-rat(101709490) ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
- domestic guinea pig(100719036) ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
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