ALDH3A1
aldehyde dehydrogenase 3 family, member A1
Synonyms:
ALDH3, ALDHIII
Species:
Human ALDH3A1 (218), Mouse Aldh3a1 (11670), Rat Aldh3a1 (25375), dog ALDH3A1 (489526), domestic cat ALDH3A1 (101096364), sheep ALDH3A1 (101108502), naked mole-rat Aldh3a1 (101699453), cow ALDH3A1 (281617), domestic guinea pig Aldh3a1 (100729236)
UniProtKB ID:
Gene ID:
- Human(218) Summary: Aldehyde dehydrogenases oxidize various aldehydes to the corresponding acids. They are involved in the detoxification of alcohol-derived acetaldehyde and in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation. The enzyme encoded by this gene forms a cytoplasmic homodimer that preferentially oxidizes aromatic and medium-chain (6 carbons or more) saturated and unsaturated aldehyde substrates. It is thought to promote resistance to UV and 4-hydroxy-2-nonenal-induced oxidative damage in the cornea. The gene is located within the Smith-Magenis syndrome region on chromosome 17. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Sep 2008]
- Mouse(11670) aldehyde dehydrogenase family 3, subfamily A1
- Rat(25375) aldehyde dehydrogenase 3 family, member A1
- dog(489526) aldehyde dehydrogenase 3 family, member A1
- domestic cat(101096364) aldehyde dehydrogenase 3 family, member A1
- sheep(101108502) aldehyde dehydrogenase 3 family, member A1
- naked mole-rat(101699453) aldehyde dehydrogenase 3 family, member A1
- cow(281617) aldehyde dehydrogenase 3 family, member A1
- domestic guinea pig(100729236) aldehyde dehydrogenase 3 family, member A1
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