AKAP5
A kinase (PRKA) anchor protein 5
Synonyms:
AKAP75, AKAP79, H21
Species:
Human AKAP5 (9495), Mouse Akap5 (238276), Rat Akap5 (171026), naked mole-rat Akap5 (101707046), sheep AKAP5 (101109277), chicken AKAP5 (428917), cow AKAP5 (281612), chicken AKAP5 (423506), dog AKAP5 (480354), domestic cat AKAP5 (101087070)
UniProtKB ID:
Gene ID:
- Human(9495) Summary: The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein binds to the RII-beta regulatory subunit of PKA, and also to protein kinase C and the phosphatase calcineurin. It is predominantly expressed in cerebral cortex and may anchor the PKA protein at postsynaptic densities (PSD) and be involved in the regulation of postsynaptic events. It is also expressed in T lymphocytes and may function to inhibit interleukin-2 transcription by disrupting calcineurin-dependent dephosphorylation of NFAT. [provided by RefSeq, Jul 2008]
- Mouse(238276) A kinase (PRKA) anchor protein 5
- Rat(171026) A kinase (PRKA) anchor protein 5
- naked mole-rat(101707046) A kinase (PRKA) anchor protein 5
- sheep(101109277) A kinase (PRKA) anchor protein 5
- chicken(428917) A kinase (PRKA) anchor protein 5
- cow(281612) A kinase (PRKA) anchor protein 5
- chicken(423506) A kinase (PRKA) anchor protein 5
- dog(480354) A kinase (PRKA) anchor protein 5
- domestic cat(101087070) A kinase (PRKA) anchor protein 5
- domestic guinea pig(100717568) A kinase (PRKA) anchor protein 5
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