ADRBK1
adrenergic, beta, receptor kinase 1
Synonyms:
BARK1, BETA-ARK1, GRK2
Species:
Human ADRBK1 (156), Mouse Adrbk1 (110355), Rat Adrbk1 (25238), naked mole-rat Adrbk1 (101708906), domestic cat ADRBK1 (101101082), cow ADRBK1 (282682), dog ADRBK1 (483701), domestic guinea pig Adrbk1 (100732560), sheep ADRBK1 (101108265), chicken ADRBK1 (426000)
UniProtKB ID:
Gene ID:
- Human(156) Summary: The product of this gene phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta-adrenergic and related G-protein-coupled receptors. Abnormal coupling of beta-adrenergic receptor to G protein is involved in the pathogenesis of the failing heart. [provided by RefSeq, Jul 2008]
- Mouse(110355) adrenergic receptor kinase, beta 1
- Rat(25238) adrenergic, beta, receptor kinase 1
- naked mole-rat(101708906) adrenergic, beta, receptor kinase 1
- domestic cat(101101082) adrenergic, beta, receptor kinase 1
- cow(282682) adrenergic, beta, receptor kinase 1
- dog(483701) adrenergic, beta, receptor kinase 1
- domestic guinea pig(100732560) adrenergic, beta, receptor kinase 1
- sheep(101108265) adrenergic, beta, receptor kinase 1
- chicken(426000) adrenergic, beta, receptor kinase 1
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-GRK2 antibody, Mouse monoclonal, clone 3A10, purified from hybridoma cell culture,
Species Reactivity
bovine, human, rat
Application
immunoprecipitation (IP)
microarray
western blot
microarray
western blot
Anti-ARBK1 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
western blot
western blot
Anti-phospho-GRK2 (pSer685) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
western blot
western blot
Anti-phospho-GRK2 (pSer29) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-BARK1/GRK2 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
canine, human, mouse, rat
Application
ELISA
western blot
western blot
Proteins
Product Number
Description
Species
GRK2, active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human