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Merck

ACVRL1

activin A receptor type II-like 1

Synonyms:
ACVRLK1, ALK-1, ALK1, HHT, HHT2, ORW2, SKR3, TSR-I
Species:
Human ACVRL1 (94), Mouse Acvrl1 (11482), Rat Acvrl1 (25237), domestic cat ACVRL1 (101097406), chicken ACVRL1 (100857446), sheep ACVRL1 (101114095), dog ACVRL1 (477603), Horse ACVRL1 (100061313), domestic cat ACVRL1 (100135773), cow ACVRL1 (534536) ...More
UniProtKB ID:
P37023, A6NGA8
Gene ID:
  • Human(94) Summary: This gene encodes a type I cell-surface receptor for the TGF-beta superfamily of ligands. It shares with other type I receptors a high degree of similarity in serine-threonine kinase subdomains, a glycine- and serine-rich region (called the GS domain) preceding the kinase domain, and a short C-terminal tail. The encoded protein, sometimes termed ALK1, shares similar domain structures with other closely related ALK or activin receptor-like kinase proteins that form a subfamily of receptor serine/threonine kinases. Mutations in this gene are associated with hemorrhagic telangiectasia type 2, also known as Rendu-Osler-Weber syndrome 2. [provided by RefSeq, Jul 2008]
  • Mouse(11482) activin A receptor, type II-like 1
  • Rat(25237) activin A receptor type II-like 1
  • domestic cat(101097406) activin A receptor type II-like 1
  • chicken(100857446) activin A receptor type II-like 1
  • sheep(101114095) activin A receptor type II-like 1
  • dog(477603) activin A receptor type II-like 1
  • Horse(100061313) activin A receptor type II-like 1
  • domestic cat(100135773) activin A receptor type II-like 1
  • cow(534536) activin A receptor type II-like 1
  • naked mole-rat(101709807) activin A receptor type II-like 1
  • Zebrafish(266753) activin A receptor type II-like 1
  • domestic guinea pig(100716392) activin A receptor type II-like 1

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Proteins

Product Number
Description
Species
A0476
Activin Receptor-Like Kinase 1/Fc Chimera human, >90% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder, suitable for cell culture,
Species
human