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Merck

ABCD3

ATP-binding cassette, sub-family D (ALD), member 3

Synonyms:
ABC43, PMP70, PXMP1, ZWS2
Species:
Human ABCD3 (5825), Mouse Abcd3 (19299), Rat Abcd3 (25270), cow ABCD3 (526059), domestic cat ABCD3 (101100069), dog ABCD3 (479939), domestic guinea pig Abcd3 (100725969), chicken ABCD3 (424487), naked mole-rat Abcd3 (101702609), Domestic Rabbit ABCD3 (100351172) ...More
UniProtKB ID:
P28288, D3DT46, Q15271, Q6NUN5, Q96DA3, Q9H529
Gene ID:
  • Human(5825) Summary: The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. This peroxisomal membrane protein likely plays an important role in peroxisome biogenesis. Mutations have been associated with some forms of Zellweger syndrome, a heterogeneous group of peroxisome assembly disorders. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]
  • Mouse(19299) ATP-binding cassette, sub-family D (ALD), member 3
  • Rat(25270) ATP-binding cassette, subfamily D (ALD), member 3
  • cow(526059) ATP-binding cassette, sub-family D (ALD), member 3
  • domestic cat(101100069) ATP-binding cassette, sub-family D (ALD), member 3
  • dog(479939) ATP-binding cassette, sub-family D (ALD), member 3
  • domestic guinea pig(100725969) ATP-binding cassette, sub-family D (ALD), member 3
  • chicken(424487) ATP-binding cassette, sub-family D (ALD), member 3
  • naked mole-rat(101702609) ATP-binding cassette, sub-family D (ALD), member 3
  • Domestic Rabbit(100351172) ATP-binding cassette, sub-family D (ALD), member 3
  • Horse(100058542) ATP-binding cassette, sub-family D (ALD), member 3
  • sheep(101118659) ATP-binding cassette, sub-family D (ALD), member 3

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Antibodies

Product Number
Description
Species Reactivity
Application
SAB2500013
Anti-ABCD3 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human, mouse, rat
Application
ELISA
flow cytometry
immunohistochemistry
SAB4200181
Anti-PMP70 antibody, Mouse monoclonal, clone 70-18, purified from hybridoma cell culture,
Species Reactivity
human, mouse, rat
Application
immunofluorescence
western blot
P0090
Anti-PMP70−Atto 488 antibody produced in rabbit, 1.5-3 mg/mL, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human, mouse, rat
Application
immunofluorescence
P0497
Anti-PMP70 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human, mouse, rat
Application
immunofluorescence
immunoprecipitation (IP)
western blot