PARP1
poly (ADP-ribose) polymerase 1
Synonyms:
ADPRT, ADPRT 1, ADPRT1, ARTD1, PARP, PARP-1, PPOL, pADPRT-1
Species:
Human PARP1 (142), Mouse Parp1 (11545), Rat Parp1 (25591), Thale Cress PARP1 (817690), chicken PARP1 (396199), Zebrafish parp1 (560788), sheep PARP1 (100135697), domestic cat PARP1 (101081434), Horse PARP1 (100058523), dog PARP1 (490385) ...More
UniProtKB ID:
Gene ID:
- Human(142) Summary: This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. [provided by RefSeq, Jul 2008]
- Mouse(11545) poly (ADP-ribose) polymerase family, member 1
- Rat(25591) poly (ADP-ribose) polymerase 1
- Thale Cress(817690) poly [ADP-ribose] polymerase 2
- chicken(396199) poly (ADP-ribose) polymerase 1
- Zebrafish(560788) poly (ADP-ribose) polymerase family, member 1
- sheep(100135697) poly (ADP-ribose) polymerase 1
- domestic cat(101081434) poly (ADP-ribose) polymerase 1
- Horse(100058523) poly (ADP-ribose) polymerase 1
- dog(490385) poly (ADP-ribose) polymerase 1
- domestic guinea pig(100733925) poly (ADP-ribose) polymerase 1
- naked mole-rat(101703207) poly (ADP-ribose) polymerase 1
- cow(286764) poly (ADP-ribose) polymerase 1
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-PARP antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human
Application
immunofluorescence
microarray
western blot
microarray
western blot
Anti-PARP (Cleaved-Asp214) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse
Application
ELISA
western blot
western blot
Rabbit anti-PARP1 Antibody, Affinity Purified, Powered by Bethyl Laboratories, Inc.,
Species Reactivity
human
Application
western blot
Anti-PARP1 antibody produced in rabbit, IgG fraction of antiserum,
Species Reactivity
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Application
western blot
Anti-PARP (Cleaved-Gly215) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
ELISA
western blot
western blot