Request a Sample for Cell Lysis or DNA Digestion

The production process of adeno-associated virus (AAV) vectors involves a midstream step that combines cell lysis and nuclease treatment.

Detergents, such as zwitterionic non-ionic surfactants, are used in biomanufacturing processes for a variety of applications including viral inactivation and cell lysis. Our Deviron^® portfolio of sustainable detergents should be considered as a primary alternative to TRITON™ X-100 by all biologics manufacturers.

In viral vector purification, free nucleic acid not only poses a threat to patient safety but also decreases product yield. Our Benzonase^® portfolio helps remove this unwanted DNA and RNA from your process, even in high salt concentrations with our NEW GMP grade Benzonase^® Salt Tolerant endonuclease.