- Development of a second generation palladium-catalyzed cycloalkenylation and its application to bioactive natural product synthesis.
Development of a second generation palladium-catalyzed cycloalkenylation and its application to bioactive natural product synthesis.
Natural product communications (2013-08-29)
Masahiro Toyota
PMID23980435
ABSTRACT
A novel palladium-catalyzed intramolecular oxidative alkylation of unactivated olefins is described. This protocol was devised to solve one of the drawbacks of the original palladium-catalyzed cycloalkenylation that we developed. We call this new procedure the 'second generation palladium-catalyzed cycloalkenylation'. This protocol has been applied to the total syntheses of cis-195A, trans-195A, boonein, scholareins A, C, D, and alpha-skytanthine.
MATERIALS
Product Number
Brand
Product Description
Palladium, foil, not light tested, 100x100mm, thickness 0.025mm, as rolled, 99.99+%
Palladium, foil, not light tested, 25x25mm, thickness 0.00075mm, permanent polyester support, 99.75%
Palladium, foil, not light tested, 25x25mm, thickness 0.006mm, 99.95%
Palladium, foil, not light tested, 25x25mm, thickness 0.025mm, as rolled, 99.99+%
Palladium, foil, 8mm disks, thickness 0.50mm, as rolled, 99.95%
Palladium, wire reel, 1m, diameter 0.125mm, hard, 99.95%
Palladium, wire reel, 0.1m, diameter 0.25mm, hard, 99.95%
Palladium, wire reel, 1m, diameter 0.25mm, hard, 99.95%
Palladium, wire reel, 0.2m, diameter 0.5mm, as drawn, 99.95%
Palladium, tube, 120mm, outside diameter 6mm, inside diameter 5mm, wall thickness 0.5mm, as drawn, 99.95%
Palladium, wire reel, 10m, diameter 0.025mm, as drawn, 99.9%
Palladium, wire reel, 1m, diameter 0.25mm, as drawn, 99.99+%
Palladium, wire reel, 0.05m, diameter 1.0mm, hard, 99.95%
Palladium, wire reel, 0.2m, diameter 1.0mm, hard, 99.95%
Palladium, wire reel, 2m, diameter 0.025mm, as drawn, 99.9%
Palladium, wire reel, 5m, diameter 0.05mm, as drawn, 99.9%
Palladium, wire reel, 20m, diameter 0.025mm, as drawn, 99.9%
Palladium, wire reel, 0.5m, diameter 0.25mm, as drawn, 99.99+%
Palladium, tube, 200mm, outside diameter 2.0mm, inside diameter 1.6mm, wall thickness 0.2mm, as drawn, 99.95%
Palladium, wire reel, 25m, diameter 0.125mm, hard, 99.95%
Palladium, wire reel, 0.1m, diameter 0.125mm, hard, 99.95%
Palladium, wire reel, 5m, diameter 0.25mm, hard, 99.95%
Palladium, wire reel, 2m, diameter 0.25mm, as drawn, 99.99+%
Palladium, wire reel, 0.5m, diameter 0.02mm, as drawn, 99.95%
Palladium, wire reel, 10m, diameter 0.25mm, hard, 99.95%
Palladium, wire reel, 0.5m, diameter 0.05mm, as drawn, 99.9%
Palladium, wire reel, 5m, diameter 0.125mm, hard, 99.95%
Palladium, foil, light tested, 100x100mm, thickness 0.025mm, as rolled, 99.95%
Palladium, foil, light tested, 100x100mm, thickness 0.025mm, as rolled, 99.99+%
Palladium, foil, light tested, 100x100mm, thickness 0.047mm, as rolled, 99.95%