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  • Hypothyroidism-related onycholysis with Aureobasidium pullulans colonization successfully treated with antifungal therapy.

Hypothyroidism-related onycholysis with Aureobasidium pullulans colonization successfully treated with antifungal therapy.

Clinical and experimental dermatology (2012-03-24)
M Arabatzis
ABSTRACT

This is a report, the first to my knowledge, of secondary nail-apparatus involvement by Aureobasidium pullulans in a patient with onycholysis related to hypothyroidism. Complete cure of the lesions was seen after 2 weeks of itraconazole and 2 months of local bifonazole therapy. This case raises concern about the extent of involvement of this yeast in onycholysis of diverse clinical aetiologies.

MATERIALS
Product Number
Brand
Product Description

Supelco
Bifonazole, Pharmaceutical Secondary Standard; Certified Reference Material
Sigma-Aldrich
Bifonazole, ≥98% (HPLC)
Bifonazole, European Pharmacopoeia (EP) Reference Standard