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P7876

Sigma-Aldrich

DL-Norephedrine hydrochloride

≥99%

Synonym(s):

(±)-Phenylpropanolamine hydrochloride, erythro-2-Amino-1-phenyl-1-propanol hydrochloride, DL-erythro-2-Amino-1-phenyl-1-propanol hydrochloride, DL-Phenylpropanolamine hydrochloride

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About This Item

Linear Formula:
C6H5CH(OH)CH(NH2)CH3 · HCl
CAS Number:
154-41-6
Molecular Weight:
187.67
Beilstein:
3914299
EC Number:
205-826-7
MDL number:
MFCD00013019
UNSPSC Code:
12352116
PubChem Substance ID:
24898881
NACRES:
NA.25
Pricing and availability is not currently available.

Quality Level

200

Assay

≥99%

form

powder

mp

194-196 °C (lit.)

SMILES string

Cl.C[C@@H](N)[C@@H](O)c1ccccc1

InChI

1S/C9H13NO.ClH/c1-7(10)9(11)8-5-3-2-4-6-8;/h2-7,9,11H,10H2,1H3;1H/t7-,9-;/m1./s1

InChI key

DYWNLSQWJMTVGJ-PRCZDLBKSA-N

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Biochem/physiol Actions

Mixed-acting sympathomimetic amine.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H302,H336

Hazard Classifications

Acute Tox. 4 Oral - STOT SE 3

Target Organs

Central nervous system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
MKCQ9692
115K0718
100F0393
091F0298
075F0385

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J Sullivan et al.
European urology, 36 Suppl 1, 89-95 (1999-07-07)
Many patients with incontinence do not need surgery - for these patients symptoms can often be considerably improved by conservative measures, including drugs. Several different pharmacological actions are potentially useful depending on the underlying cause of the incontinence: a) Detrusor
Mona Karout et al.
Journal of neurochemistry, 139(5), 782-794 (2016-06-04)
The natural neurosteroid allopregnanolone exerts beneficial effects in animal models of neurodegenerative diseases, nervous system injury and peripheral neuropathies. It not only has anti-apoptotic activity, but also promotes proliferation of progenitor cells. With respect to using it as a therapeutic
Amal Kaddoumi et al.
Journal of pharmaceutical and biomedical analysis, 34(3), 643-650 (2004-05-07)
A high performance liquid chromatographic method for the determination of phenylpropanolamine (PPA) in human plasma and rat's brain and blood microdialysates using fluorescence (FL) detection after precolumn derivatization with 4-(4,5-diphenyl-1H-imidazole-2-yl)benzoyl chloride (DIB-Cl) is described. PPA was extracted from plasma samples
R Dowse et al.
Journal of pharmaceutical sciences, 72(9), 1018-1020 (1983-09-01)
A high-performance liquid chromatographic analysis of phenylpropanolamine in human serum and urine without prior derivatization is presented. Using direct UV detection the method is sufficiently sensitive to detect 25 ng of drug/ml of serum or urine; the coefficients of variation
Tung Si Ho et al.
Journal of chromatographic science, 44(6), 308-316 (2006-08-04)
Different organic borates, phosphates, sulphates, and carboxylic acids are evaluated as extraction carriers in three-phase liquid-phase microextraction (LPME). Hydrophilic basic drugs form ion-pairs with the carriers and are extracted as ion-pair complexes into an organic liquid membrane of n-octanol or
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Chromatograms

application for HPLC

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