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P3531

Sigma-Aldrich

1,2-Distearoyl-sn-glycero-3-phosphoethanolamine

≥99%

Synonym(s):

1,2-Dioctadecanoyl-sn-glycero-3-phosphoethanolamine, 3-sn-Phosphatidylethanolamine, 1,2-distearoyl, L-β,γ-Distearoyl-α-cephalin

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About This Item

Empirical Formula (Hill Notation):
C41H82NO8P
CAS Number:
1069-79-0
Molecular Weight:
748.07
Beilstein:
1730641
EC Number:
213-963-9
MDL number:
MFCD00036777
UNSPSC Code:
12352207
PubChem Substance ID:
24898422
NACRES:
NA.77

Quality Level

100

Assay

≥99%

form

powder

lipid type

phospholipids

storage temp.

−20°C

SMILES string

CCCCCCCCCCCCCCCCCC(=O)OC[C@H](COP(O)(=O)OCCN)OC(=O)CCCCCCCCCCCCCCCCC

InChI

1S/C41H82NO8P/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-40(43)47-37-39(38-49-51(45,46)48-36-35-42)50-41(44)34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2/h39H,3-38,42H2,1-2H3,(H,45,46)/t39-/m1/s1

InChI key

LVNGJLRDBYCPGB-LDLOPFEMSA-N

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Application


  • Injectable Composite Hydrogels Embedded with Gallium-Based Liquid Metal Particles for Solid Breast Cancer Treatment via Chemo-Photothermal Combination.: This article presents the use of DSPE in developing injectable composite hydrogels. These hydrogels are embedded with liquid metal particles to provide a dual-mode treatment approach combining chemotherapy and photothermal therapy for breast cancer (Lee et al., 2024).

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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Shawn Stapleton et al.
ACS nano, 12(8), 7583-7600 (2018-07-14)
Nanomedicine drug delivery systems are capable of transporting significant payloads to solid tumors. However, only a modest increase in antitumor efficacy relative to the standard of care has been observed. In this study, we demonstrate that a single dose of
Ching-Hsiang Fan et al.
ACS synthetic biology, 6(11), 2021-2027 (2017-09-26)
We developed an ultrasound-chemical hybrid tool to precisely manipulate cellular activities. A focused ultrasound coupled with gas-filled microbubbles was used to rapidly trigger the influx of membrane-impermeable chemical dimerizers into living cells to regulate protein dimerization and location without inducing
Elisabeth Mamelle et al.
European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 274(2), 729-736 (2016-10-08)
Goals of cochlear implantation have shifted from complete insertion of the cochlear electrode array towards low traumatic insertion with minimally invasive techniques. The aim of this study was first to evaluate, in a guinea pig model of cochlear implantation, the
Ting Zhang et al.
International journal of pharmaceutics, 515(1-2), 449-459 (2016-11-05)
Polysialic acid (PSA) serves as a hydrophilic polymer and affords conjugated biologically active molecules a longer circulation time in vivo. Furthermore, PSA could potentially target tumor tissues and help achieve better curative effects. In this study, PSA was conjugated with
Kanwaldeep K Gill et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 79(2), 276-284 (2011-05-18)
The objective of the present study was to evaluate the potential of paclitaxel loaded micelles fabricated from PEG(5000)-DSPE as a sustained release system following pulmonary delivery. PEG(5000)-DSPE micelles containing paclitaxel were prepared by solvent evaporation technique followed by investigation of
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