P0483

Anti-Potassium Channel SK2 antibody produced in rabbit

affinity isolated antibody, lyophilized powder

• Synonym(s): Apamin-Sensitive Conductance Ca2+-Dependent K+ Channel, KCa2, Kcnn2, SKCa2
• MDL number: MFCD02097223
• UNSPSC Code: 12352203
• NACRES: NA.41

Properties

• biological source: rabbit
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: lyophilized powder
• species reactivity: human, rat
• technique(s): western blot (chemiluminescent): 1:200 using rat brain membranes
• UniProt accession no.: Q9H2S1
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: rat ... Kcnn2(54262)

Description

General description

Potassium calcium-activated channel subfamily N member 2 (KCNN2) or SK2 is expressed in rat Purkinje cells. The gene encoding this protein is localized on rat chromosome 18q11.

Immunogen

synthetic peptide corresponding to amino acids 542-559 of rat potassium channel SK2.

Application

Anti-Potassium Channel SK2 (Apamin-Sensitive Conductance Ca²⁺-Dependent K⁺ Channel, KCa2, Kcnn2, SKCa2) antibody produced in rabbit has been used for immunohistochemistry and immunofluorescence.

Biochem/physiol Actions

Potassium calcium-activated channel subfamily N member 2 (KCNN2) or SK2 has a role in the modulation of intrinsic excitability of neurons and Purkinje cells. It also has a role in synaptic transmission and plasticity. SK2 promotes hippocampus-dependent learning and memory in the mammalian brain.

Physical form

Lyophilized at 0.3-1.4 mg/mL from phosphate buffered saline, pH 7.4, containing 1% bovine serum albumin and 0.025% - 0.050% sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 2
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable