15821

Klebsiella Selective Supplement

suitable for microbiology

• Synonym(s): Carbenicillin, α-Carboxybenzylpenicillin solution
• Empirical Formula (Hill Notation): C₁₇H₁₈N₂O₆S
• Molecular Weight: 378.40
• EC Number: 225-171-0
• MDL number: MFCD00242604
• UNSPSC Code: 41171614
• PubChem Substance ID: 329750863
• NACRES: NA.85

Properties

• sterility: sterile
• form: powder
• shelf life: limited shelf life, expiry date on the label
• application(s): clinical testing; environmental; food and beverages; microbiology
• storage temp.: 2-8°C
• suitability: Klebsiella spp.
• SMILES string: CC1(C)S[C@@H]2[C@H](NC(=O)C(C(O)=O)c3ccccc3)C(=O)N2[C@H]1C(O)=O
• InChI: 1S/C17H18N2O6S/c1-17(2)11(16(24)25)19-13(21)10(14(19)26-17)18-12(20)9(15(22)23)8-6-4-3-5-7-8/h3-7,9-11,14H,1-2H3,(H,18,20)(H,22,23)(H,24,25)/t9?,10-,11+,14-/m1/s1
• InChI key: FPPNZSSZRUTDAP-UWFZAAFLSA-N

Description

Application

For selective isolation and detection of Klebsiella species.

Biochem/physiol Actions

Carbenicillin is an ampicillin analog with structure related to benzyl penicillin. It is effective against Gram-negative bacteria and exhibits limited activity against Gram-positive bacteria. Carbenicillin binds and inhibits the enzymes involved in the synthesis of bacterial cell wall. Since carbenicillin is less sensitive to β-lactamases than ampicillin, it is effective against ampicillin-resistant bacteria. It has superior stability at low pH and acts as a selection agent. Effective concentration of carbenicillin: 50 to 100 μg/ml.

Components

(per vial, sufficient for 500 ml medium)
Carbenicillin 25 mg

Safety Information

• Pictograms: GHS08
• Signal Word: Danger
• Hazard Statements: H317,H334
• Precautionary Statements: P261 - P272 - P280 - P284 - P302 + P352 - P333 + P313
• Hazard Classifications: Resp. Sens. 1 - Skin Sens. 1
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves