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32-0290

Sigma-Aldrich

Urea

SAJ first grade, ≥98.0%

Synonym(s):

Carbamide, Carbonyldiamide

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About This Item

Linear Formula:
NH2CONH2
CAS Number:
Molecular Weight:
60.06
Beilstein:
635724
MDL number:
UNSPSC Code:
12352111
PubChem Substance ID:

grade

SAJ first grade

Assay

≥98.0%

form

solid

availability

available only in Japan

mp

132-135 °C (lit.)

density

1.335 g/mL at 25 °C (lit.)

SMILES string

NC(N)=O

InChI

1S/CH4N2O/c2-1(3)4/h(H4,2,3,4)

InChI key

XSQUKJJJFZCRTK-UHFFFAOYSA-N

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Application

Used for the denaturation of proteins and as a mild solubilization agent for insoluble or denatured proteins. Useful for renaturing proteins from samples already denatured with 6 M guanidine chloride such as inclusion bodies. May be used with guanidine hydrochloride and dithiothreitrol (DTT) in the refolding of denatured proteins into their native or active form.

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

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Manuela Maria Iftime et al.
Carbohydrate polymers, 223, 115040-115040 (2019-08-21)
The paper reports new soil conditioner systems obtained by in situ hydrogelation of chitosan with salicylaldehyde in the presence of urea fertilizer, designed to address both fertilization and water retention of the soil. The new systems were structural, supramolecular and
Giora van Straten et al.
PloS one, 9(6), e100077-e100077 (2014-06-20)
The detoxification of ammonia occurs mainly through conversion of ammonia to urea in the liver via the urea cycle and glutamine synthesis. Congenital portosystemic shunts (CPSS) in dogs cause hyperammonemia eventually leading to hepatic encephalopathy. In this study, the gene
Stephanie Dille et al.
PloS one, 9(7), e103220-e103220 (2014-07-30)
Chlamydia grows inside a cytosolic vacuole (the inclusion) that is supplied with nutrients by the host through vesicular and non-vesicular transport. It is unclear in many respects how Chlamydia organizes this transport. One model posits that the Chlamydia-induced fragmentation of
Anne-Roos S Frenay et al.
PloS one, 10(6), e0129732-e0129732 (2015-06-11)
Some diseases associated with a temporary deterioration in kidney function and/or development of proteinuria show an apparently complete functional remission once the initiating trigger is removed. While it was earlier thought that a transient impairment of kidney function is harmless
Hannah M Kaneb et al.
Human molecular genetics, 24(5), 1363-1373 (2014-10-26)
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disorder characterized by the selective death of motor neurons. Causative mutations in the global RNA-processing proteins TDP-43 and FUS among others, as well as their aggregation in ALS patients, have identified defects

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