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20-158

Sigma-Aldrich

0.5M EDTA

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About This Item

UNSPSC Code:
41116012
eCl@ss:
32160405
NACRES:
NA.41

form

liquid

Quality Level

manufacturer/tradename

Upstate®

shipped in

wet ice

General description

Ethylenediaminetetraacetic acid (EDTA) is an aminopolycarboxylic acid (APCAs). It serves as a metal chelating agent. EDTA is an anticoagulant, which prevents blood clotting by chelating calcium from the blood. EDTA-mediated platelet aggregation leads to pseudothrombocytopenia.. It is used to treat poisoning caused by heavy metals such as mercury and lead.

Application

0.5M EDTA has been used as a constituent of Dulbecco′s phosphate‐buffered saline (DPBS) for resuspension of trypsinized Human embryonic kidney 293T (HEK293T) cells in ataxin‐1 aggregation kinetics assay. It may also be used in chromatin immunoprecipitation (ChIP) assays.

Physical form

0.5M EDTA, pH 8.0.

Storage and Stability

1 year at 4°C

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2

Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Eveliina Repo et al.
Water research, 47(14), 4812-4832 (2013-07-19)
Due to the excellent chelating properties of aminopolycarboxylic acid (APCAs), they can be used for the removal of metals from contaminated waters. This paper reviews the research results obtained for both commercial and self-prepared adsorbents functionalized with four most common
Simon Finnegan et al.
Advances in wound care, 4(7), 415-421 (2015-07-15)
Significance: Methods employed for preventing and eliminating biofilms are limited in their efficacy on mature biofilms. Despite this a number of antibiofilm formulations and technologies incorporating ethylenediaminetetraacetic acid (EDTA) have demonstrated efficacy on in vitro biofilms. The aim of this
Hae Lyun Ahn et al.
The Korean journal of internal medicine, 17(1), 65-68 (2002-05-17)
EDTA-dependent pseudothrombocytopenia (PTCP) is the phenomenon of a spurious low platelet count due to EDTA-induced aggregation of platelets. Since the failure to recognize EDTA-dependent PTCP may result in incorrect diagnosis and inappropriate treatment, the recognition of this phenomenon is very
Neha Dhar et al.
Biotechnology and bioengineering, 117(2), 362-371 (2019-11-12)
Protein abnormalities are the major cause of neurodegenerative diseases such as spinocerebellar ataxia (SCA). Protein misfolding and impaired degradation leads to the build-up of protein aggregates inside the cell, which may further cause cellular degeneration. Reducing levels of either the

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