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1.04527

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3-Methyl-2-benzothiazolinone-hydrazonehydrochloride

GR for analysis Reag. Ph Eur

Synonym(s):

3-Methyl-2-benzothiazolinone-hydrazonehydrochloride, MBTH

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About This Item

Empirical Formula (Hill Notation):
C8H10ClN3S
CAS Number:
4338-98-1
Molecular Weight:
215.70
UNSPSC Code:
12352107
EC Index Number:
224-393-5
NACRES:
NA.05

Agency

reag. Ph. Eur.

Quality Level

100

form

solid

potency

149 mg/kg LD50, oral (Rat)
12300 mg/kg LD50, skin (Rabbit)

pH

3-4 (20 °C, 4 g/L in H2O)

bulk density

748 kg/m3

storage temp.

15-25°C

InChI

1S/C8H9N3S.Cl/c1-11-6-4-2-3-5-7(6)12-8(11)10-9;/h2-5H,9H2,1H3;/b10-8+;

InChI key

WAGARHVUZQWORV-VRTOBVRTSA-N

Application

  • Kinetic spectrophotometric determination of ethamsylate in dosage forms.: The research describes a kinetic spectrophotometric method for determining ethamsylate using 3-Methyl-2-benzothiazolinone-hydrazone hydrochloride. The method is efficient for analyzing ethamsylate in various pharmaceutical formulations (El-Enany et al., 2007).
  • Spectrophotometric determination of dobutamine hydrochloride using 3-methylbenzothiazolin-2-one hydrazone.: This study provides a spectrophotometric method for dobutamine hydrochloride analysis, highlighting the utility of 3-Methyl-2-benzothiazolinone-hydrazone hydrochloride in analytical chemistry for pharmaceutical applications (el-Kommos, 1987).
  • Microdetermination of D-amino acids and D-amino acid oxidase activity with 3,methyl-2-benzothiazolone hydrazone hydrochloride.: This research introduces a microdetermination method for D-amino acids and D-amino acid oxidase activity using 3-Methyl-2-benzothiazolinone-hydrazone hydrochloride, contributing to biochemical analysis techniques (Soda, 1968).

Analysis Note

Assay (argentometric): ≥ 99
Identity (IR-spectrum): passes test
pH-value (0.4 %, water): 3 - 4
Melting point: about 270
Sulfated ash: ≤ 0.1 %
Loss on Drying (105°C): ≤ 1.0 %
Suitability for determination of aldehydes: passes test

Pictograms

Skull and crossbones
GHS06

Signal Word

Danger

Hazard Statements

H301

Hazard Classifications

Acute Tox. 3 Oral

Storage Class Code

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

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