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Key Documents

93690

Sigma-Aldrich

L-Tryptophan ethyl ester hydrochloride

≥99.0% (AT)

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About This Item

Empirical Formula (Hill Notation):
C13H16N2O2 · HCl
CAS Number:
Molecular Weight:
268.74
Beilstein:
3919010
EC Number:
MDL number:
UNSPSC Code:
12352209
PubChem Substance ID:
NACRES:
NA.22

Assay

≥99.0% (AT)

form

powder

optical activity

[α]20/D +10±1°, c = 2% in H2O

reaction suitability

reaction type: solution phase peptide synthesis

mp

220-225 °C (dec.)

application(s)

peptide synthesis

SMILES string

Cl.CCOC(=O)[C@@H](N)Cc1c[nH]c2ccccc12

InChI

1S/C13H16N2O2.ClH/c1-2-17-13(16)11(14)7-9-8-15-12-6-4-3-5-10(9)12;/h3-6,8,11,15H,2,7,14H2,1H3;1H/t11-;/m0./s1

InChI key

PESYCVVSLYSXAK-MERQFXBCSA-N

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Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Kento Takayama et al.
Journal of natural medicines, 75(1), 116-128 (2020-10-21)
Indole is produced from dietary tryptophan by tryptophanase in intestinal bacteria, such as Escherichia coli. In the liver, indole is converted into indoxyl sulfate, a uremic toxin and risk factor for chronic kidney disease (CKD). Probiotics and prebiotics are currently
S Fukushima et al.
Urological research, 10(3), 115-118 (1982-01-01)
The effect of partial cystectomy on the occurrence of pre-neoplastic lesions, papillary or nodular hyperplasia (PN hyperplasia), of the bladder in male F344 rats was studied in an experiment in which bladder carcinogens and promoters were given to the rats
R P Kwok et al.
Neuroendocrinology, 45(4), 267-273 (1987-04-01)
In this study we investigated the effect of insulin on striatal 5-hydroxytryptamine and tryptamine in streptozotocin-diabetic and in normal rats. Streptozotocin-diabetic rats show a reduction in rat striatal tryptophan, 5-hydroxytryptamine, and 5-hydroxyindole acetic acid, an effect observed at 7 or
A J Jonas et al.
The Journal of clinical investigation, 84(1), 200-204 (1989-07-01)
Tryptophan ethyl ester, a lipid-soluble tryptophan derivative, was used to bypass defective gastrointestinal neutral amino acid transport in a child with Hartnup disease. The child's baseline tryptophan concentrations in serum (20 +/- 6 microM) and cerebrospinal fluid (1.0 +/- 0.2
F Kilár et al.
Electrophoresis, 16(8), 1510-1518 (1995-08-01)
Enantiomers can be separated by using human serum transferrin as a chiral phase. With the help of the native protein we were able to separate enantiomers with high efficiency, using a low ionic strength 2-(N-morpholino)ethanesulfonic acid (MES) buffer, pH 6

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