205869

Palladium(II) acetate

reagent grade, 98%

• Synonym(s): Pd(OAc)₂, [Pd(OAc)₂]₃
• Linear Formula: Pd(OCOCH₃)₂
• CAS Number: 3375-31-3
• Molecular Weight: 224.51
• Beilstein: 6086766
• EC Number: 222-164-4
• MDL number: MFCD00012453
• UNSPSC Code: 12161600
• PubChem Substance ID: 24852356
• NACRES: NA.22

Properties

• grade: reagent grade
• Quality Level: 200
• Assay: 98%
• form: powder
• reaction suitability: core: palladium; reaction type: Buchwald-Hartwig Cross Coupling Reaction; reaction type: Heck Reaction; reaction type: Hiyama Coupling; reaction type: Negishi Coupling; reaction type: Sonogashira Coupling; reaction type: Stille Coupling; reaction type: Suzuki-Miyaura Coupling; reagent type: catalyst
• mp: 216.3-223.7 °C (dec.)
• SMILES string: CC(O[Pd]OC(C)=O)=O
• InChI: 1S/2C2H4O2.Pd/c2*1-2(3)4;/h2*1H3,(H,3,4);/q;;+2/p-2
• InChI key: YJVFFLUZDVXJQI-UHFFFAOYSA-L

Description

General description

[Pd(OAc)₂]₃ is a palladium coordination complex and a heterogenous metal catalyst that is widely used in organic synthesis such as transmetalation, insertion, oxidative addition, direct homocoupling of aryl halides, Buchwald-Hartwig reaction of C-N bond formation, reduction of alkynes, and reductive elimination reactions. It is also employed as a starting material for the synthesis of other Pd(II) compounds as well as for the preparation of active palladium catalysts for Suzuki-Miyaura cross-coupling and C-H functionalization reactions.

Application

Application Guide for Palladium Catalyzed Cross-Coupling Reactions

[Pd(OAc)₂]₃ can be used as a:

• Catalyst for the regioselective anti-hydrochlorination of the terminal and internal alkynes.
• Precursor to prepare a heterogeneous palladium complex catalyst for the Heck-Coupling reaction and Sonogashira cross-coupling reaction.

Safety Information

• Pictograms: GHS05,GHS07,GHS09
• Signal Word: Danger
• Hazard Statements: H317,H318,H410
• Precautionary Statements: P261 - P272 - P273 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Skin Sens. 1A
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 2
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves