T6424
Trypsin from human pancreas
salt-free, lyophilized powder, vial of ≥1,000 BAEE units
Synonym(s):
Serine Protease 1
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About This Item
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biological source
human pancreas
Quality Level
form
salt-free, lyophilized powder
packaging
vial of ≥1,000 BAEE units
storage temp.
−20°C
Gene Information
human ... PRSS1(5644) , PRSS2(5645) , PRSS3(5646)
General description
The trypsin molecule has two domains: one is related to the enzyme active site and the tryptophan residues; the other is related to the 8-anilinonaphthalene-1-sulfonate binding.
Trypsin is a serine protease. The pancreas produce the precursor trypsinogen and secretes it to the intestine. Trypsinogen is converted to trypsin by enterokinase in the intestinal mucous membrane.
Application
Trypsin has been used in a study to assess the similarities between the hepatitis E virus and human astrovirus. Trypsin has also been used in a study to characterize a unique technique for culturing primary adult human epithelial progenitor, or stem, cells.
Unit Definition
One BAEE unit will produce a ΔA253 of 0.001 per min at pH 7.6 at 25 °C using BAEE as substrate. Reaction volume = 3.2 mL (1 cm light path).
Quantity
Minimum 1,000 BAEE units/vial
Analysis Note
Protein determined by E1%/280.
Other Notes
View more information on trypsin at www.sigma-aldrich.com/enzymeexplorer
inhibitor
Product No.
Description
Pricing
substrate
Product No.
Description
Pricing
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - STOT SE 3
Target Organs
Respiratory system
Storage Class Code
11 - Combustible Solids
WGK
WGK 1
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Certificates of Analysis (COA)
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