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258R-2

Sigma-Aldrich

Glial Fibrillary Acidic Protein (GFAP) (SP78) Rabbit Monoclonal Antibody

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About This Item

UNSPSC Code:
12352106
NACRES:
NA.41

biological source

rabbit

Quality Level

100
500

conjugate

unconjugated

antibody form

culture supernatant

antibody product type

primary antibodies

clone

SP78, monoclonal

description

For In Vitro Diagnostic Use in Select Regions (See Chart)

form

buffered aqueous solution

species reactivity

human

packaging

vial of 0.1 mL concentrate (258R-24)
vial of 0.5 mL concentrate (258R-25)
bottle of 1.0 mL predilute (258R-27)
vial of 1.0 mL concentrate (258R-26)
bottle of 7.0 mL predilute (258R-28)

manufacturer/tradename

Cell Marque™

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500

isotype

IgG

control

brain

shipped in

wet ice

storage temp.

2-8°C

visualization

cytoplasmic

Gene Information

human ... GFAP(2670)

General description

Anti-GFAP antibody detects astrocytes, Schwann cells, satellite cells, enteric glial cells, and some groups of ependymal cells. This marker is mainly used to distinguish neoplasms of astrocytic origin from other neoplasms in the central nervous system.

Linkage

GFAP Positive Control Slides, Product No. 258S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Physical form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Preparation Note

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Other Notes

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Legal Information

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

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Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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N Funata
The Bulletin of Tokyo Medical and Dental University, 32(1), 9-18 (1985-03-01)
The GFAP-positive cells in the five human anterior pituitaries obtained at autopsy were investigated immunohistochemically and ultramicroscopically. The GFAP-positive cells varied in number from case to case and were identical with the so-called stellate cell. The stellate cells were also
A Regner et al.
Journal of neurotrauma, 18(8), 783-792 (2001-08-31)
Trauma is the leading cause of death in individuals between the ages of 1 and 44 years. And, in the case of severe head injury mortality can reach as high as 35-70%. Despite this fact, there has been little progress
G Viale et al.
Virchows Archiv. A, Pathological anatomy and histopathology, 418(4), 339-348 (1991-01-01)
Immunostaining for glial fibrillary acidic protein (GFAP) identifies a minor subpopulation of immunoreactive myoepithelial cells in the normal resting human breast. The GFAP-immunoreactive cells also express a panel of myoepithelial cell markers, including cytokeratin 14 (CK 14), vimentin, smooth-muscle-specific actin
K R Jessen et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 3(11), 2206-2218 (1983-11-01)
The similarities between the enteric nervous system of the gut and the central nervous system (CNS), both of which function as complex integrative nervous networks, include striking ultrastructural similarities between the glia of the enteric nervous system and the astrocytic
F Giangaspero et al.
Acta neuropathologica, 103(2), 152-156 (2002-01-26)
We report on two children with cerebral gliomas showing extensive lipomatous change of tumor cells. One tumor was a large mass occupying the temporal and occipital lobes of the left hemisphere; the other was a cystic lesion with a mural
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