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Key Documents

09-1680

Sigma-Aldrich

2-Ethoxyethanol

SAJ special grade, ≥99.0%

Synonym(s):

Ethyl glycol, Ethylene glycol monoethyl ether

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About This Item

Linear Formula:
C2H5OCH2CH2OH
CAS Number:
Molecular Weight:
90.12
Beilstein:
1098271
EC Number:
MDL number:
UNSPSC Code:
12352112
PubChem Substance ID:

grade

SAJ special grade

vapor density

3.1 (vs air)

vapor pressure

3.8 mmHg ( 20 °C)

Assay

≥99.0%

form

liquid

autoignition temp.

460 °F

expl. lim.

14 %

availability

available only in Japan

refractive index

n20/D 1.407 (lit.)

bp

135 °C (lit.)

mp

−90 °C (lit.)

density

0.93 g/mL at 25 °C (lit.)

SMILES string

CCOCCO

InChI

1S/C4H10O2/c1-2-6-4-3-5/h5H,2-4H2,1H3

InChI key

ZNQVEEAIQZEUHB-UHFFFAOYSA-N

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Signal Word

Danger

Hazard Statements

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Flam. Liq. 3 - Repr. 1B

Storage Class Code

3 - Flammable liquids

WGK

WGK 2

Flash Point(F)

104.0 °F - closed cup

Flash Point(C)

40 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Rui-Sheng Wang et al.
Industrial health, 45(4), 574-578 (2007-09-20)
Ethylene glycol monoethyl ether (EGEE) can cause damage to testes and sperm, and its metabolites are believed to play an important role in its toxicity. Aldehyde dehydrogenase 2 (ALDH2) is involved in the metabolism of this chemical. To investigate whether
Isaac A Adedara et al.
Human & experimental toxicology, 29(10), 801-812 (2010-02-23)
The effects of ethylene glycol monoethyl ether (EGEE) on the antioxidant systems of the testes and epididymal spermatozoa were investigated in rats at dose levels of 0, 100, 200 and 400 mg kg(-1) body weight (bw) administered orally by gavage
Douglas J Fort et al.
Drug and chemical toxicology, 25(3), 293-308 (2002-08-14)
Currently, no standardized and well-validated alternative models exist for screening for progesterone-responsive endocrine disrupting chemicals (EDCs). Because of this, a rapid assay for evaluating progestin/antiprogestin activity using Xenopus oocyte germinal vesicle breakdown (GVBD) as a model was evaluated. Five compounds
Gargi Bagchi et al.
International journal of andrology, 31(2), 269-274 (2008-01-09)
Methoxyacetic acid (MAA), the active biological oxidation product of the industrial solvent ethylene glycol monomethyl ether (EGME), causes acute toxicity in several species including humans. MAA primarily affects tissues with rapidly dividing cells and high rates of energy metabolism, including
David J Lockley et al.
Toxicology and applied pharmacology, 180(2), 74-82 (2002-04-24)
Percutaneous absorption and cutaneous metabolism of 2-ethoxyethanol were assessed in vivo and with an in vitro flow-through diffusion system. Topical application of undiluted (14)C-ethoxyethanol to occluded rat skin in vivo resulted in 25% of the dose being absorbed after 24

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