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Key Documents

MAB837

Sigma-Aldrich

Anti-Papillomavirus Antibody, 1, 6, 11, 16, 18, 31, clone 1H8

clone 1H8, Chemicon®, from mouse

Synonym(s):

HPV

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

mouse

antibody form

purified antibody

antibody product type

primary antibodies

clone

1H8, monoclonal

species reactivity

human

manufacturer/tradename

Chemicon®

technique(s)

ELISA: suitable
immunohistochemistry: suitable
western blot: suitable

isotype

IgG

shipped in

wet ice

Specificity

Human papillomavirus proteins - HPV-1, HPV-6, HPV-11, HPV-16, HPV-18 and HPV-31.

Immunogen

Epitope: 1, 6, 11, 16, 18, 31
SDS-disrupted bovine papillomavirus type 1.

Application

Anti-Papillomavirus Antibody, 1, 6, 11, 16, 18, 31, clone 1H8 is an antibody against Papillomavirus for use in ELISA, WB, IH.
Immunohistochemistry

ELISA

Western Blot

Optimal working dilutions must be determined by end user.
Research Category
Infectious Diseases
Research Sub Category
Infectious Diseases - Viral

Physical form

Format: Purified
Liquid in 0.02M PB 0.25M NaCl, and 0.1% sodium azide, pH 7.6.

Storage and Stability

Maintain at 2-8°C.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Identification of the bovine papillomavirus L1 gene product using monoclonal antibodies.
Cowsert, L M, et al.
Virology, 165, 613-615 (1988)
A A McBride et al.
Proceedings of the National Academy of Sciences of the United States of America, 97(10), 5534-5539 (2000-05-11)
Bovine papillomavirus type 1 (BPV-1) induces fibropapillomas in its natural host and can transform fibroblasts in culture. The viral genome is maintained as an episome within fibroblasts, which has allowed extensive genetic analyses of the viral functions required for DNA
L M Cowsert et al.
Journal of the National Cancer Institute, 79(5), 1053-1057 (1987-11-01)
Monoclonal antibodies (MAbs) were generated against sodium dodecyl sulfate-disrupted bovine papillomavirus type 1 (BPV-1). When screened by enzyme-linked immunosorbent assay (ELISA) on intact and disrupted BPV-1, -2, and deer papillomavirus, three patterns of reactivity were defined: reactivity only with intact
Determinants of autoantibody induction by conjugated papillomavirus virus-like particles.
Bryce Chackerian, Petra Lenz, Douglas R Lowy, John T Schiller
Journal of immunology (Baltimore, Md. : 1950) (1950)
Anna Yemelyanova et al.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 26(2), 268-274 (2012-09-22)
While cervical cancer screening relies on cervical cytology and high-risk human papillomavirus (HPV) detection, the histologic diagnosis, and specifically lesion grade, is the main parameter that drives clinical management of screen-positive women. Morphologically diagnosed squamous intraepithelial lesions (SIL/CIN) regress spontaneously

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