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A Benzylideneacetophenone Derivative Induces Apoptosis of Radiation-Resistant Human Breast Cancer Cells via Oxidative Stress.

Biomolecules & therapeutics (2017-05-31)
Jeong Eon Park, Mei Jing Piao, Kyoung Ah Kang, Kristina Shilnikova, Yu Jae Hyun, Sei Kwan Oh, Yong Joo Jeong, Sungwook Chae, Jin Won Hyun
RESUMEN

Benzylideneacetophenone derivative (1E)-1-(4-hydroxy-3-methoxyphenyl) hept-1-en-3-one (JC3) elicited cytotoxic effects on MDA-MB 231 human breast cancer cells-radiation resistant cells (MDA-MB 231-RR), in a dose-dependent manner, with an IC

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Sigma-Aldrich
Diacetato de 2′,7′-diclorofluoresceína, ≥97%
Sigma-Aldrich
1,3-Bis(diphenylphosphino)propane, 97%
Sigma-Aldrich
JC-1, powder or solid (Crystals)
Sigma-Aldrich
Amyloid Protein Non-Aβ Component, ≥80% (HPLC)