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  • Understanding trans platinum complexes as potential antitumor drugs beyond targeting DNA.

Understanding trans platinum complexes as potential antitumor drugs beyond targeting DNA.

Journal of inorganic biochemistry (2012-07-24)
A G Quiroga
ABSTRACT

This focused review is devoted to our advances in developing trans platinum complexes as antitumoral complexes, in particular those bearing aliphatic amines. It includes some fundamental aspects of the understanding of non conventional metallodrug mechanism. The perspective is arranged by those fundamental aspects and within each section only the most successful examples have been included and also those in which clearly SAR's (structure activity relationships) have been observed.

MATERIALS
Product Number
Brand
Product Description

Platinum, tube, 50mm, outside diameter 6mm, inside diameter 5.6mm, wall thickness 0.2mm, as drawn, 99.95%
Platinum, tube, 500mm, outside diameter 0.5mm, inside diameter 0.42mm, wall thickness 0.04mm, as drawn, 99.95%
Platinum, tube, 500mm, outside diameter 1.2mm, inside diameter 1.0mm, wall thickness 0.1mm, as drawn, 99.95%
Platinum, wire reel, 0.05m, diameter 0.8mm, annealed, may be used as one component of a thermocouple, 99.99%
Platinum, wire reel, 0.05m, diameter 0.6mm, as drawn, 99.99+%
Platinum, wire reel, 0.1m, diameter 0.5mm, as drawn, 99.99+%
Platinum, foil, 50x50mm, thickness 0.125mm, as rolled, 99.99+%
Platinum, foil, 0.1m coil, thickness 0.15mm, coil width .9mm, as rolled, 99.99%
Platinum, foil, 0.05m coil, thickness 0.029mm, coil width .34mm, annealed, 99.99%
Platinum, foil, 0.2m coil, thickness 0.029mm, coil width .34mm, annealed, 99.99%
Platinum, foil, 0.1m coil, thickness 0.025mm, coil width 1.6mm, as rolled, 99.95%
Sigma-Aldrich
Platinum, nanopowder, 200 nm particle size (SEM), 99.9% (metals basis)
Platinum, wire reel, 0.1m, diameter 0.125mm, as drawn, 99.95%
Platinum, wire reel, 0.1m, diameter 0.175mm, as drawn, 99.95%
Platinum, foil, 10mm disks, thickness 0.0075mm, as rolled, 99.95%
Platinum, foil, 4mm disks, thickness 0.025mm, as rolled, 99.99+%
Platinum, foil, 8mm disks, thickness 0.01mm, as rolled, 99.95%
Platinum, wire reel, 0.5m, diameter 0.25mm, annealed, may be used as one component of a thermocouple, 99.99%
Platinum, foil, 0.5m coil, thickness 0.025mm, coil width 8mm, as rolled, 99.95%
Platinum, wire reel, 0.1m, diameter 0.002mm, wollaston, 99.9%
Platinum, wire reel, 0.2m, diameter 1.0mm, hard, 99.95%
Platinum, foil, 0.2m coil, thickness 0.025mm, coil width .4mm, as rolled, 99.95%
Platinum, wire reel, 0.1m, diameter 0.25mm, annealed, may be used as one component of a thermocouple, 99.99%
Platinum, foil, 0.2m coil, thickness 0.05mm, coil width 1mm, as rolled, 99.99%
Platinum, wire reel, 0.1m, diameter 1.0mm, hard, 99.95%
Platinum, foil, 8mm disks, thickness 0.004mm, as rolled, 99.95%
Platinum, insulated wire, 2m, conductor diameter 0.025mm, insulation thickness 0.005mm, polyester insulation, 99.99%
Platinum, insulated wire, 1m, conductor diameter 0.025mm, insulation thickness 0.001mm, PTFE (polytetrafluoroethylene) insulation, 99.999%
Platinum, foil, not light tested, 50x50mm, thickness 0.0075mm, as rolled, 99.95%
Platinum, insulated wire, 0.5m, conductor diameter 0.025mm, insulation thickness 0.001mm, PTFE (polytetrafluoroethylene) insulation, 99.999%