Skip to Content
Merck
All Photos(1)

Key Documents

View All Documentation

SML3349

Sigma-Aldrich

SGC8158N

≥98% (HPLC)

Synonym(s):

9-((3aR,4R,6S,6aS)-6-(((4-(((4’-Chloro-[1,1’-biphenyl]-3-yl)methyl)amino)butyl)thio)methyl)-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxol-4-yl)-9H-purin-6-amine, 9-((3aR,4R,6S,6aS)-6-((4-((4’-Chlorobiphenyl-3-yl)methylamino)butylthio)methyl)-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxol-4-yl)-9H-purin-6-amine

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Empirical Formula (Hill Notation):
C30H35ClN6O3S
Molecular Weight:
595.16
UNSPSC Code:
12352200
NACRES:
NA.32

Quality Level

100

Assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

2-8°C

SMILES string

ClC1=CC=C(C2=CC(CNCCCCSC[C@@H]3[C@@H]4[C@H]([C@H](N5C6=C(C(N)=NC=N6)N=C5)O3)OC(C)(O4)C)=CC=C2)C=C1

Biochem/physiol Actions

SGC8158N is a negative control probe for selective and cell-active PRMT7 inhibitor SGC8158.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Magdalena M Szewczyk et al.
Nature communications, 11(1), 2396-2396 (2020-05-16)
Protein arginine methyltransferases (PRMTs) regulate diverse biological processes and are increasingly being recognized for their potential as drug targets. Here we report the discovery of a potent, selective, and cell-active chemical probe for PRMT7. SGC3027 is a cell permeable prodrug

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service