SAB4301725

Anti-PKD2L1

affinity isolated antibody

• Synonym(s): PCL, PKD2L, PKDL, TRPP3
• UNSPSC Code: 12352203
• NACRES: NA.41

Properties

• biological source: rabbit
• Quality Level: 100
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous glycerol solution
• species reactivity: human
• technique(s): immunohistochemistry: 1:20-1:100
• accession no.: NP_057196
• UniProt accession no.: Q9P0L9
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... PKD2L1(9033)

Description

General description

PKD2L1 (polycystin 2 like 1, transient receptor potential cation channel) is also known as polycystin-L/ transient receptor potential polycystin-3 (TRPP3). It is expressed in brain, kidney, heart, skeletal muscle, spleen, testis, retina and in the bipolar neurons in the tongue taste buds. TRPP3 is present on the surface membrane and/or endoplasmic reticulum membrane of cells. It belongs to the PKD2 gene family. PKD2L1 is mapped to human chromosome 10q25.

Immunogen

Synthetic peptide of human PKD2L1

Biochem/physiol Actions

PKD2L1 (polycystin 2 like 1, transient receptor potential cation channel) participates in hedgehog signaling, intestinal development and sour tasting. It controls ciliary Ca2⁺ concentration. Mutations in PKD2 results in autosomal dominant kidney disease (ADPKD).

Features and Benefits

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Physical form

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Safety Information

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable