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Key Documents

L3140

Sigma-Aldrich

Lipoteichoic acid from Streptococcus pyogenes

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About This Item

CAS Number:
MDL number:
UNSPSC Code:
12352211
NACRES:
NA.25

biological source

Streptococcus pyogenes

Quality Level

form

lyophilized powder

functional group

phospholipid

lipid type

polymerizable lipids

shipped in

ambient

storage temp.

2-8°C

Related Categories

Application

Lipoteichoic acid (LTA) is a complex component of cell walls of Gram-positive bacteria that are involved in a wide range of cell processes such as the stimulation of immune responses and cell signaling pathways. LTA differs between species of gram-positive bacteria. Lipoteichoic acid from Streptococcus pyogenes may be used to compare its structure, immunogenicity and functions versus other bacterial LTAs.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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J P Himanen et al.
Journal of general microbiology, 139(11), 2659-2665 (1993-11-01)
To evaluate the suitability of Bacillus subtilis as a production host of heterologous proteins for pharmaceutical purposes, we assessed the biological activity of this bacterium and its major cell envelope components, lipoteichoic acid (LTA) and peptidoglycan-teichoic acid complex (PG-TA) in
Hun Yi Park et al.
International journal of pediatric otorhinolaryngology, 76(4), 475-479 (2012-02-07)
Change in matrix metalloproteinases (MMPs) and regulation of their tissue inhibitors of metalloproteinases (TIMPs) could play certain role in the pathogenesis of otitis media. This study was designed to evaluate the modulation of MMPs and TIMPs in middle ear epithelium
Jun Ho Jeon et al.
Comparative immunology, microbiology and infectious diseases, 35(4), 363-374 (2012-03-27)
At allergic inflammation, cross-linking of FcɛRI with multivalent antigen-bound IgE triggers the signaling pathways via activation of protein kinase C (PKC) and mobilization of intracellular Ca(2+) leading to the production of various mediators such as interleukin-6 (IL-6). Accumulating reports demonstrated
Induction of intestinal pro-inflammatory immune responses by lipoteichoic acid.
Zadeh M, Khan MW, Goh YJ, et al.
Journal of Inflammation, 9, 7-7 (2012)
Ning Xie et al.
Bulletin du cancer, 99(5), E55-E63 (2012-04-24)
To investigate the therapeutic efficacy of lipoteichoic acid of Bifidobacterium (BLTA) in combination with 5-fluorouracil (5-FU) treatment on the mice bearing inoculated hepatoma-22 (H(22)) cells and the effects of BLTA on immunological regulation of organism, and explore its mechanisms. Tumor-bearing

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