- Low-cost, flexible polymer arrays for long-term neuronal culture.
Low-cost, flexible polymer arrays for long-term neuronal culture.
Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference (2013-02-01)
N Catherine Hogan, Giovanni Talei-Franzesi, Omar Abudayyeh, Andrew Taberner, Ian Hunter
PMID23366014
ABSTRACT
Conducting polymers are promising materials for fabrication of microelectrode arrays for both neural stimulation and recording. Our ability to engineer the morphology and composition of polypyrrole together with its suitability as an electrically addressable tissue/cell substrate have been used to develop an inexpensive, disposable three-dimensional polymeric array for use in neuronal culture and drug discovery. These arrays could be interfaced with a fixed, parallel stimulation and optical imaging system, amenable to automated handling and data analysis.
MATERIALS
Product Number
Brand
Product Description
Sigma-Aldrich
Polypyrrole, doped, conductivity 0.5-1.5 S/cm (pressed pellet, typical), extent of labeling: ~5 wt. % loading, coated on titanium dioxide
Sigma-Aldrich
Polypyrrole, doped, conductivity 30 S/cm (bulk), extent of labeling: 20 wt. % loading, composite with carbon black