- Redox-neutral indole annulation cascades.
Redox-neutral indole annulation cascades.
Journal of the American Chemical Society (2011-02-02)
Michael C Haibach, Indubhusan Deb, Chandra Kanta De, Daniel Seidel
PMID21280625
ABSTRACT
Aminobenzaldehydes react with indoles in an unprecedented cascade reaction. This acid-catalyzed redox-neutral annulation proceeds via a condensation/1,5-hydride shift/ring-closure sequence. Polycyclic azepinoindoles and related compounds are obtained in a single step with good to excellent yields.
MATERIALS