Skip to Content
Merck
All Photos(1)

Documents

P5386

Sigma-Aldrich

Poly-γ-benzyl-L-glutamate

mol wt 70,000-150,000

Synonym(s):

PBLG

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

CAS Number:
25014-27-1
MDL number:
MFCD00166357
UNSPSC Code:
12352202
NACRES:
NA.26

form

powder

mol wt

70,000-150,000

color

white to light yellow

storage temp.

−20°C

InChI

1S/C12H15NO4/c13-10(12(15)16)6-7-11(14)17-8-9-4-2-1-3-5-9/h1-5,10H,6-8,13H2,(H,15,16)/t10-/m0/s1

InChI key

BGGHCRNCRWQABU-JTQLQIEISA-N

Looking for similar products? Visit Product Comparison Guide

Application


  • Hydrogen bond formation may enhance RDC-based discrimination of enantiomers.: This research explores the impact of hydrogen bond formation on residual dipolar couplings (RDC) in the discrimination of enantiomers. Poly-y-benzyl-L-glutamate (PBLG) is used as a chiral alignment medium, enhancing the sensitivity and resolution of NMR spectroscopy for enantiomeric analysis (Sager et al., 2024).

  • Potential and performance of anisotropic (19)F NMR for the enantiomeric analysis of fluorinated chiral active pharmaceutical ingredients.: This study highlights the use of PBLG as an alignment medium in anisotropic 19F NMR spectroscopy for analyzing chiral pharmaceutical compounds. The research demonstrates improved enantiomeric discrimination and quantification, crucial for pharmaceutical development (Gouilleux et al., 2024).

  • Block Sequence Effects on the Self-Assembly Behaviors of Polypeptide-Based Penta-Block Copolymer Hydrogels.: This study investigates the self-assembly behavior of block copolymer hydrogels containing PBLG. The research shows how block sequence affects the mechanical properties and potential applications of these hydrogels in biomedical fields (Wang et al., 2024).

  • Liquid crystalline composite hydrogels with large pH-triggered anisotropic swelling for embolotherapy.: This research explores the development of liquid crystalline hydrogels incorporating PBLG for use in embolotherapy. The hydrogels demonstrate significant pH-responsive swelling, making them suitable for targeted medical applications (Zhang et al., 2024).

Analysis Note

Molecular weight based on viscosity.

Other Notes

For additional technical information on polyamino acids please visit the Polyamino acid FAQ resource.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Electrospun Poly(γ-Benzyl-l-Glutamate) and Its Alkali-Treated Meshes: Their Water Wettability and Cell-Adhesion Potential.
Hakamada Y, Ohgushi N, et al.
Journal of Biomaterials Science. Polymer Edition, 28(1), 757-765 (2011)
Wei Huang et al.
Journal of materials science. Materials in medicine, 22(4), 853-863 (2011-03-05)
Recently, many efforts have been devoted to investigating the application of functionalized micelles as targeted drug delivery carriers. In this study, glycyrrhetinic acid (GA, a liver targeting ligand) modified poly(ethylene glycol)-b-poly(γ-benzyl L-glutamate) micelles were prepared and evaluated as a potential
Hana Robson Marsden et al.
Journal of the American Chemical Society, 132(7), 2370-2377 (2010-01-30)
A new class of peptide has been created, polypeptide-b-designed peptides, which unites the useful qualities of the two constituent peptide types. We demonstrate the synthesis and self-assembly possibilities of this class of peptide chimera with a series of amphiphilic polypeptide-b-designed
Zeinab Serhan et al.
Chemical communications (Cambridge, England), 46(35), 6599-6601 (2010-08-20)
NAD 2D NMR spectroscopy using chiral mesophases made of poly-gamma-benzyl-l-glutamate and pyridine allowed us to evaluate, for the first time, the natural site-specific enantio-isotopomeric excesses at each methylene group of linoleic acid, a central, essential PUFA precursor of all conjugated
Rajeswari Ravichandran et al.
Biomaterials, 33(3), 846-855 (2011-11-04)
Tissue engineering and nanotechnology have enabled engineering of nanostructured materials to meet the current challenges in bone treatment owing to rising occurrence of bone diseases, accidental damages and defects. Poly(L-lactic acid)/Poly-benzyl-L-glutamate/Collagen (PLLA/PBLG/Col) scaffolds were fabricated by electrospinning and nanohydroxyapatite (n-HA)
View All Related Papers

Articles

Poly(Amino Acid) Block Copolymers for Drug Delivery and other Biomedical Applications

Humankind has utilized protein materials throughout its existence, starting with the use of materials such as wool and silk for warmth and protection from the elements and continuing with the use of recombinant DNA techniques to synthesize proteins with unique and useful properties.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service