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P33429

Sigma-Aldrich

4-Phenylpyridine

97%

Synonym(s):

γ-Phenylpyridine, 1-Benzylhydrazine dihydrochloride, p-Phenylpyridine

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About This Item

Empirical Formula (Hill Notation):
C11H9N
CAS Number:
939-23-1
Molecular Weight:
155.20
Beilstein:
110490
EC Number:
213-357-4
MDL number:
MFCD00006420
UNSPSC Code:
12352100
PubChem Substance ID:
24898403
NACRES:
NA.22

Assay

97%

form

crystals

bp

274-275 °C (lit.)

mp

69-73 °C (lit.)

SMILES string

c1ccc(cc1)-c2ccncc2

InChI

1S/C11H9N/c1-2-4-10(5-3-1)11-6-8-12-9-7-11/h1-9H

InChI key

JVZRCNQLWOELDU-UHFFFAOYSA-N

Gene Information

human ... MMP3(4314)

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Related Categories

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H335

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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Germano Giuliani et al.
Bioorganic & medicinal chemistry, 19(7), 2242-2251 (2011-03-23)
The quinoline nucleus of the previously described 4-phenylquinoline-3-carboxamides NK(1) receptor ligands 7 has been transformed into either substituted or azole-(i.e., triazole or tetrazole) fused pyridine moieties of compounds 9 and 10, respectively, in order to obtain NK(1) receptor ligands showing
K S Hsu et al.
The Journal of pharmacology and experimental therapeutics, 279(2), 740-747 (1996-11-01)
The effect of L-deprenyl (selegiline) on the excitatory synaptic transmission was characterized in the CA1 neurons of rat hippocampal slices by using a intracellular recording technique. Superfusion of L-deprenyl (0.1-10 microM) reversibly decreased the EPSP, which was evoked by orthodromic
A D Vaz et al.
Drug metabolism and disposition: the biological fate of chemicals, 20(1), 108-112 (1992-01-01)
The binding to human placental aromatase cytochrome P-450 and resulting extent of inhibition was examined for pyridine, pyridines substituted at the 2-, 3-, or 4-positions with phenyl or benzoyl groups, and the nonpyridinic structural analogs biphenyl and benzophenone. Spectral binding
L A Carr et al.
European journal of pharmacology, 215(2-3), 285-287 (1992-05-14)
To determine whether the attenuation of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced neurotoxicity by tobacco smoke exposure is caused by inhibition of the neuronal uptake of 4-phenylpyridinium ion (MPP+), various tobacco components and a smoke extract were tested for inhibitory activity in striatal synaptosomes.
M R Gluck et al.
The Journal of biological chemistry, 269(5), 3167-3174 (1994-02-04)
We have investigated the mechanism of the inhibition of membrane-bound NADH dehydrogenase by 1-methyl-4-phenylpyridinium (MPP+) and a series of its 4'-alkyl-substituted analogs of increasing hydrophobicity, as well as their neutral, desmethyl congeners. Comparison of hydrophobicity, as measured by partition coefficients
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