302295

5-Nitro-2-thiophenecarboxaldehyde

98%

• Empirical Formula (Hill Notation): C₅H₃NO₃S
• CAS Number: 4521-33-9
• Molecular Weight: 157.15
• EC Number: 224-850-9
• MDL number: MFCD00005433
• UNSPSC Code: 12352100
• PubChem Substance ID: 24858243
• NACRES: NA.22

Properties

• Assay: 98%
• form: solid
• mp: 75-77 °C (lit.)
• solubility: acetone: soluble 1%, clear, yellow
• SMILES string: [H]C(=O)c1ccc(s1)[N+]([O-])=O
• InChI: 1S/C5H3NO3S/c7-3-4-1-2-5(10-4)6(8)9/h1-3H
• InChI key: CHTSWZNXEKOLPM-UHFFFAOYSA-N

Description

General description

Diastereoselectivity in [4+2] cycloaddition of 1-methoxy-2-methyl-3-(trimethylsiloxy)-1,3-pentadiene with 5-nitro-2-thiophenecarboxaldehyde was investigated.

Application

5-Nitro-2-thiophenecarboxaldehyde was used in preparation of 2, 3-dihydro-2-(5-nitro-2-thienyl) quinazolin-4-(1H)-ones and various novel oxime ether derivatives, anti-protozoan agents.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H315,H319,H335
• Precautionary Statements: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves