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Membrane dynamics of resting and internalin B-bound MET receptor tyrosine kinase studied by single-molecule tracking.

FEBS open bio (2017-09-15)
Marie-Lena I E Harwardt, Phoebe Young, Willem M Bleymüller, Timo Meyer, Christos Karathanasis, Hartmut H Niemann, Mike Heilemann, Marina S Dietz
RESUMEN

The human MET receptor tyrosine kinase contributes to vertebrate development and cell proliferation. As a proto-oncogene, it is a target in cancer therapies. MET is also relevant for bacterial infection by

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Disolución salina tamponada con fosfatos de Dulbecco, 10×, Modified, without calcium chloride and magnesium chloride, liquid, sterile-filtered, suitable for cell culture
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Triton X-100, laboratory grade