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  • Determination of 2,6-dimethyl-4-(2'-nitrosophenyl)-3,5-pyridinedicarboxylic acid dimethylester in nifedipine by derivative UV-spectrophotometry in bulk material and pharmaceutical forms.

Determination of 2,6-dimethyl-4-(2'-nitrosophenyl)-3,5-pyridinedicarboxylic acid dimethylester in nifedipine by derivative UV-spectrophotometry in bulk material and pharmaceutical forms.

Farmaco (Societa chimica italiana : 1989) (1990-06-01)
G Carlucci, A Colanzi, P Mazzeo
RESUMEN

A method for the determination of 2,6-dimethyl-4-(2'-nitrosophenyl)-3,5-pyridinedicarboxylic acid dimethylester in nifedipine (bulk material and pharmaceutical formulations) by second-derivative ultraviolet spectrophotometry is described. The procedure is simple and rapid and gives accurate and precise results.

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USP
Nifedipine Nitrosophenylpyridine Analog, United States Pharmacopeia (USP) Reference Standard
Nifedipine impurity B, European Pharmacopoeia (EP) Reference Standard