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[Studies on chemical constituents of Galeopsis bifida].

Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica (2003-05-31)
Yong-hong Zhang, Tao Wang, Zhi-gang Lu, Han-qing Wang
RESUMEN

To investigate the chemical constituents of Galeopsis bifida. Various chromatographic techniques were employed for isolation and purification of the constituents. The structures were elucidated by chemical and spectral analyses. Ten compounds were isolated and identified as chrysoeriol(1), 5,7-dihydroxy-3',4'-dimethoxyflavone(2), hederagenin(3), daucosterol(4), martynoside(5), ajugoside(6), 8-acetyl harpagid(7), 5,7,4'-trihydroxy-3'-methoxyflavone-7-O-beta-D-glucoside(8), 5,6,7,4'-tetrahydroxyflavone-7-O-beta-D-glucoside(9) and 5,7,3',4'-tetrahydroxyflavone-7-O-beta-D-glucoside (10). Compound 6, 7 were found from genus Galeopsis for the first time and rest of compounds were found from G. bifida for the first time.

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8-Acetylharpagide, ≥85% (LC/MS-ELSD)