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Design, synthesis and structure-activity relationship of novel RXR-selective modulators.

Bioorganic & medicinal chemistry letters (2004-03-10)
Pierre-Yves Michellys, Jennifer D'Arrigo, Timothy A Grese, Donald S Karanewsky, Mark D Leibowitz, Dale A Mais, Christopher M Mapes, Anne Reifel-Miller, Deepa Rungta, Marcus F Boehm
RESUMEN

The synthesis and in vitro characterization of novel RXR-selective ligands possessing various substituted 1-benzofuran or 1-benzothiophene moieties are described.