Saltar al contenido

Plasma beta-phenylethylamine in Parkinson's disease.

Plasma beta-phenylethylamine in Parkinson's disease.

The Kurume medical journal (2001-02-24)

Y Miura

RESUMEN

Plasma beta-phenylethylamine (PEA) levels were determined in 27 patients with Parkinson's disease (PD) in order to evaluate its relation with the severity or clinical course of PD. The plasma PEA concentrations in PD patients were significantly lower (mean +/- SD, 862 +/- 554 pg/ml) than those in the control group (1765 +/- 790 pg/ml) (p < 0.0001). The concentrations of PEA in plasma did not correlate with Hoen and Yahr stage. However, in serial measurements of the PEA of 5 patients in the progressive group of the clinical course of PD, the plasma PEA levels revealed a downward trend after one or two years. On the other hand, in 3 patients of non-progressive group, the plasma PEA remained at the same level. This study suggests that plasma PEA level might reflect nigrostriatal degeneration in patients with PD.

MATERIALES

Referencia del producto

Marca

Descripción del producto

Sigma-Aldrich

Taurine, ≥99%

Sigma-Aldrich

L-Cystine, from non-animal source, meets EP testing specifications, suitable for cell culture, 98.5-101.0%

Sigma-Aldrich

Aluminum, powder, ≥91% (complexometric)

Sigma-Aldrich

Cinc, dust, <10 μm, ≥98%

Sigma-Aldrich

Magnesio, powder, ≥99%

Sigma-Aldrich

Cinc, powder, <150 μm, 99.995% trace metals basis

Sigma-Aldrich

L-Cystine, ≥98% (TLC), crystalline

Sigma-Aldrich

S-(5′-Adenosyl)-L-homocysteine, crystalline

Sigma-Aldrich

Taurine, suitable for cell culture, meets USP testing specifications

Sigma-Aldrich

Mercury, ACS reagent, 99.9995% trace metals basis

SAFC

L-Cystine

Sigma-Aldrich

Copper, powder, 99.999% trace metals basis

Sigma-Aldrich

Tin, ≥99%, powder

Sigma-Aldrich

Silicon, powder, −325 mesh, 99% trace metals basis

Sigma-Aldrich

Copper, foil, thickness 0.25 mm, 99.98% trace metals basis

Sigma-Aldrich

Raney^®-Nickel, W.R. Grace and Co. Raney^® 2800, slurry, in H₂O, active catalyst

Sigma-Aldrich

Copper, powder, <425 μm, 99.5% trace metals basis

Sigma-Aldrich

Calcium, granular, 99%

Sigma-Aldrich

Manganese, powder, ≥99.9% trace metals basis

Sigma-Aldrich

Copper, wire, diam. 1.0 mm, ≥99.9%

Sigma-Aldrich

Tin, powder, <150 μm, 99.5% trace metals basis

Sigma-Aldrich

Magnesio, purum, for Grignard reactions, ≥99.5%, turnings

Sigma-Aldrich

Silicon, wafer (single side polished), <100>, N-type, contains no dopant, diam. × thickness 2 in. × 0.5 mm

Sigma-Aldrich

Magnesio, ribbon, ≥99.0% Mg basis

Sigma-Aldrich

L-Cystine, ≥99.7% (TLC)

Sigma-Aldrich

Nickel, nanopowder, <100 nm avg. part. size, ≥99% trace metals basis

Sigma-Aldrich

DL-Homocysteine, ≥95% (titration)

Sigma-Aldrich

Cobalt, powder, 2 μm particle size, 99.8% trace metals basis

Sigma-Aldrich

Cinc, nanopowder, 40-60 nm avg. part. size, ≥99% trace metals basis

Sigma-Aldrich

Cinc, foil, thickness 0.25 mm, 99.9% trace metals basis