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  • [Current problems in the quality control of pharmaceutical preparations manufactured in pharmacies II. Paracetamol contraining preparations].

[Current problems in the quality control of pharmaceutical preparations manufactured in pharmacies II. Paracetamol contraining preparations].

Acta pharmaceutica Hungarica (2007-06-20)
Bálint Sinkó, Gergely Völgyi, Péter Horváth, Novák Krisztina Takaćsne
RESUMEN

In our previous paper identification methods using chemical reactions and TLC are described for the active ingredients of pharmaceutical preparations in Formula Normales (FoNo VII.). Present paper introduces the development and validation of analytical methods suitable for quantitative determination of paracetamol containing dosage forms in FoNo VII. Titrimetric methods, UV spectroscopy and HPLC are used for assay of paracetamol and accompanying components (e.g. codeine, papaverine, caffeine and acetylsalicylic acid) in these preparations.

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Ethylmorphine solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®