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Dissociation of the behavioural and endocrine effects of lysine vasopressin by tryptic digestion.

British journal of pharmacology (1972-05-01)
D de Wied, H M Greven, S Lande, A Witter
RESUMEN

1. Lysine vasopressin induces resistance to extinction of active avoidance behaviour (De Wied, 1971).2. Digestion of lysine vasopressin with trypsin almost completely destroys the pressor-, antidiuretic-, oxytocic- and corticotrophin-releasing factor activities of lysine vasopressin, but does not materially influence its effect on the maintenance of an avoidance response.

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Sigma-Aldrich
[Lys8]-Vasopressin, ≥98% (HPLC)