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Synthesis of functionalized oxazolines and oxazoles with DAST and Deoxo-Fluor.

Organic letters (2000-05-11)
A J Phillips, Y Uto, P Wipf, M J Reno, D R Williams
RESUMEN

[formula: see text] A mild and highly efficient cyclization of beta-hydroxy amides to oxazolines is described using DAST and Deoxo-Fluor reagents. A one-pot protocol for the synthesis of oxazoles from beta-hydroxy amides is also presented.

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Sigma-Aldrich
(Diethylamino)sulfur trifluoride, 95%