- A bisphosphonate tweezers and clickable PEGylated PAMAM dendrons for the preparation of functional iron oxide nanoparticles displaying renal and hepatobiliary elimination.
A bisphosphonate tweezers and clickable PEGylated PAMAM dendrons for the preparation of functional iron oxide nanoparticles displaying renal and hepatobiliary elimination.
Chemical communications (Cambridge, England) (2013-08-31)
Cynthia Ghobril, Gabriela Popa, Audrey Parat, Claire Billotey, Jacqueline Taleb, Pauline Bonazza, Sylvie Begin-Colin, Delphine Felder-Flesch
PMID23991429
RESUMEN
The functionalization of superparamagnetic iron oxide nanoparticles (SPION) with PEGylated PAMAM dendrons through a bisphosphonate tweezers yielded 15 and 30 nm dendritic nano-objects stable in physiological media and showing both renal and hepatobiliary elimination.
MATERIALES